For example, such methods may include a administering a candidate compound to a subject; b comparing the level of serpina-1 polypeptides and or albumin polypeptides in a test urine sample obtained from the subject with the level of serpina-1 polypeptides and or albumin polypeptides in a control urine sample, wherein if the serpina-1 polypeptide and or albumin polypeptide levels are lower in the test urine sample than in the control urine sample, the candidate compound is a compound that treats preeclampsia.
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